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近年研究成果

1. Sun, Peng.; Wang, Qianwen.; Yuan, B.; Zhu, Qinjun.; Jiang, Bin.; Li, Conggang.; Lan, Wenxian.; Cao, Chunyang.; Zhang, Xu.; Liu, Maili., Monitoring alkaline transitions of yeast iso-1 cytochrome c at natural isotopic abundance using trimethyllysine as a native NMR probe. Chemical Communications 2018, 54 (89), 12630-12633.

2. Zhang, Liang., Chai, Xin., Sun, Peng., Zhu, Qin. Jun., Zhang, Xu., Liu, Mai. Li., Characterization of the aggregated pattern of CHAPS using solvent paramagnetic relaxation enhancements. Colloids and Surfaces a-Physicochemical and Engineering Aspects 2018, 555, 332-338. 

3.Li, Tao., Li, Shuangli., Liang, Chunjie., Zhu, Jiang., Liu, Maili., Yang, Yunhuang., Chemical shift assignments of RHE_RS02845, a NTF2-like domain-containing protein from Rhizobium etli. Biomolecular Nmr Assignments 2018, 12 (2), 249-252. 

4.  Li, Shuangli., Hu, Rui., Yao, Haijie., Long, Dong., Luo, Fan., Zhou, Xin., Zhang, Xu., Liu, Maili., Zhu, Jiang., Yang, Yunhuang., Characterization of the interaction interface and conformational dynamics of human TGIF1 homeodomain upon the binding of consensus DNA. Biochimica Et Biophysica Acta-Proteins and Proteomics 2018, 1866 (10), 1021-1028. 

5. Zhang, Zeting., Jiang, Xin., Xu, Danrui., Zheng, Wenwen., Liu, Maili., Li, Conggang., Calcium accelerates SNARE-mediated lipid mixing through modulating alpha-synuclein membrane interaction. Biochimica Et Biophysica Acta-Biomembranes 2018, 1860 (9), 1848-1853. 

6. Yu, G.; Chen, X.; Mao, S.; Liu, M.; Du, Y., Tracing the micro-process of co-aggregation between binary surfactants in aqueous solutions using H-1 NMR. Colloids and Surfaces a-Physicochemical and Engineering Aspects 2018, 550, 132-137. 

7. Kou, Xinhui., Liu, Yixiang., Li, Conggang., Liu, Maili., Jiang, Ling., Dimerization and Conformational Exchanges of the Receiver Domain of Response Regulator PhoB from Escherichia coli. Journal of Physical Chemistry B 2018, 122 (22), 5749-5757. 

8. Liu, Jun., Du, Youru., Mao, Shizhen., Liu, Maili., Micellar Exchange Kinetics of Quaternary Ammonium Type Gemini Surfactants Monitored by Nuclear Magnetic Resonance. Chinese Journal of Chemical Physics 2018, 31 (2), 159-164. 

9. Wang, Wanping., Shao, Limin., Yuan, Bin., Zhang, Xu., Liu, Maili., Determining the number of chemical species in nuclear magnetic resonance data matrix by taking advantage of collinearity and noise. Analytica Chimica Acta 2018, 1022, 20-27. 

10. Yang, Shengjun., Zeng, Qingbin., Guo, Qianni., Chen, Shizhen., Liu, Hongbin., Liu, Maili., McMahon, Michael T., Zhou, Xin., Detection and differentiation of Cys, Hcy and GSH mixtures by F-19 NMR probe. Talanta 2018, 184, 513-519. 

11. He, Ting., Li, Shuangli., Hu, Rui., Ramelot, Theresa A.., Kennedy, Michael A.., Yang, Yunhuang., Zhu, Jiang., Liu, Maili., Chemical shift assignments of Mb1858 (24-155), a FHA domain-containing protein from Mycobacterium bovis. Biomolecular Nmr Assignments 2018, 12 (1), 1-4. 

12. Huang, Xi., Yuan, Yaping., Ruan, Weiwei., Liu, Lianhua.,Liu, Maili., Chen, Shizhen.,Zhou, Xin., pH-responsive theranostic nanocomposites as synergistically enhancing positive and negative magnetic resonance imaging contrast agents. Journal of Nanobiotechnology 2018, 16. 

13. Jiang, Bin., He, Xiaomin., Yang, Yunhuang., Zhang, Xu., Zhou, Xin., Li, Conggang., Yang, Daiwen., Liu, Maili ., Suppress Sampling Truncation Artifacts in Constant-time Type Nuclear Magnetic Resonance Experiments Using Iterative Soft Thresholding Method. Chinese Journal of Analytical Chemistry 2017, 45 (12), 1888-1894. 

14. Kou, Xinhui., Liu, Xinghong., Liu, Yixiang., Li, Conggang., Liu, Maili., Jiang, Ling., Backbone resonance assignment of the response regulator protein PhoB(N) (F20D) from Escherichia coli. Biomolecular Nmr Assignments 2018, 12 (1), 133-137. 

15. Liang, Chunjie., He, Ting., Li, Tao., Yang, Yunhuang., Zhu, Jiang., Liu, Maili., Chemical shift assignments of CHU_1110: an AHSA1-like protein from Cytophaga hutchinsonii. Biomolecular Nmr Assignments 2018, 12 (1), 155-158. 

16. Liu, Yixiang., Rose, Joshua., Huang, Shaojia., Hu, Yangbo., Wu, Qiong., Wang, Dan., Li, Conggang., Liu, Maili., Zhou, Pei., Jiang, Ling., A pH-gated conformational switch regulates the phosphatase activity of bifunctional HisKA-family histidine kinases. Nature Communications 2017, 8. 

17. Wang, Sen., Lyu, Kangjie., Sun, Peng., Lu, Ang., Liu, Maili., Zhuang, Lin., Zhang, Lina., Influence of cation on the cellulose dissolution investigated by MD simulation and experiments. Cellulose 2017, 24 (11), 4641-4651 

18. Ye, Yansheng., Wu, Qiong., Zheng, Wenwen., Jiang, Bin., Pielak, Gary J.., Liu, Maili., Li, Conggang., Quantification of size effect on protein rotational mobility in cells by F-19 NMR spectroscopy. Analytical and Bioanalytical Chemistry 2018, 410 (3), 869-874. 

19. Zhu, Jiang., Li, Shuangli., Ramelot, Theresa A.., Kennedy, Michael A.., Liu, Maili., Yang, Yunhuang., Structural insights into the impact of two holoprosencephaly-related mutations on human TGIF1 homeodomain. Biochemical and Biophysical Research Communications 2018, 496 (2), 575-581. 

20. Deng, He; Sun, Xianping; Liu, Maili; Ye, Chaohui; Zhou, Xin, Entropy-based window selection for detecting dim and small infrared targets. Pattern Recognition 2017, 61, 66-77. 

21. Yu, Gang Jin; Chen, Xiao Ying; Mao, Shi Zhen; Liu, Mai Li; Du, You Ru, Hydrophobic terminal group of surfactant initiating micellization as revealed by 1 H NMR spectroscopy. Chinese Chemical Letters 2017. 

22. Zeng, Qingbin; Guo, Qianni; Yuan, Yaping; Yang, Yuqi; Zhang, Bin; Ren, Lili; Zhang, Xiaoxiao; Luo, Qing; Liu, Maili; Bouchard, Louiss., Mitochondria Targeted and Intracellular Biothiol Triggered Hyperpolarized 129Xe Magnetofluorescent Biosensor. Analytical Chemistry 2017, 2288-2295. 

23. Xu, Guohua; Cheng, Kai; Wu, Qiong; Liu, Maili; Li, Conggang, Confinement Alters the Structure and Function of Calmodulin. Angewandte Chemie 2016, 129. 

24. Wang, Xiaohua., Wang, Jie., Kamal, Ghulam Mustafa., Jiang, Bin., Sun, Peng., Zhang, Xu., Liu,Maili., Characterization and Comparison of Commercial Chinese Cereal and European Grape Vinegars Using H-1 NMR Spectroscopy Combined with Multivariate Analysis. Chinese Journal of Chemistry 2016, 34, 1183-1193.

25.  Kamal, G. M.; Wang, X. H.; Yuan, B.; Wang, J.; Sun, P.; Zhang, X.; Liu, M. L., Compositional differences among Chinese soy sauce types studied by C-13 NMR spectroscopy coupled with multivariate statistical analysis. Talant 2016, 158, 89-99. 

26. Kamal, G. M.,; Yuan, B.; Hussian, A. I.; Wang, J.; Zhang, X.; Liu, M. L., 13C-NMR-Based Metabolomic Profiling of Typical Asian Soy Sauce. Molecules 2016. 

27. Bai, J.; Cheng, K.; Liu, M. L.; Li, C. G., Impact of the alpha-Synuclein Initial Ensemble Structure on Fibrillation Pathways and Kinetics. Journal of Physical Chemistry 2016, 120(12), 3140-3147. 

28. Deng, H.; Zhong, J. P.; Ruan, W. W.; Chen, X.; Sun, X. P.; Ye, C. H.; Liu, M. L.; Zhou, X., Constant-variable flip angles for hyperpolarized media MRI. Journal of Magnetic Resonance 2016, 263, 92-100. 

29. Deng, H,; Sun, X. P.; Liu, M. L.; Ye, C. H.; Zhou, X., Infrared Small-Target Detection Using Multiscale Gray Difference Weighted Image Entropy. Ieee Transactions on Aerospace and Electronic Systems 2016, 52(1), 60-72. 

30. Feng, Y.; Zhu, H.; Zhang, X.; Wang, X.; Xu, F. Q.; Tang, H. R.; Ye, C. H.; Liu, M. L., NMR Based Cerebrum Metabonomic Analysis Reveals Simultaneous Interconnected Changes during Chick Embryo Incubation. Plos One 2016, 10(10). 

31. Guo, Q. N.; Zeng, Q. B.; Jiang, W. P,; Zhang, X. X.; Luo, Q.; Zhang, X.; Bouchard, L. S.; Liu, M. L.; Zhou, X., A Molecular Imaging Approach to Mercury Sensing Based on Hyperpolarized Xe-129 Molecular Clamp Probe. Chemistry-a European Journal 2016, 22(12), 3967-3970. 

32. Y. G.; Zhang, Z.; Feng, J. W.; Huang, C. Y.; Chen, F.; Liu, C. Y.; Liu, M. L., Simultaneous acquisition of multi-nuclei enhanced NMR/MRI by solution-state dynamic nuclear polarization. Science China-Chemistry 2016, 59(7), 830-835 

33. Majeed, M.; Hussian, A. I.; Chatha, S. A. S.; Khosa, M. K. K.; Kamal, G. M.; Kamal, M. A.; Zhang, X.; Liu, M. L., Optimization protocol for the extraction of antioxidant components from Origanum vulgare leaves using response surface methodology. Saudi Journal of Biological Sciences 2016, 23(3), 389-396. 

34. Bai, J.; Zhang, Z. T.; Liu, M. L.; Li, C. G., Alpha-synuclein-lanthanide metal ions interaction: binding sites, conformation and fibrillation. Bmc Biophysics 2016, 9. 

35. Ren, L. L.; Chen, S. Z.; Li, H. D.; Zhang, Z. Y.; Zhong, J. P.; Liu, M. L.; Zhou, X., MRI-guided liposomes for targeted tandem chemotherapy and therapeutic response prediction. Acta Biomaterialia 2016, 35, 260-268. 

36. Yang, S. J.; Jiang, W. P.; Ren, L. L.; Yuan, Y. P.; Zhang, B.; Luo, Q.; Guo, Q. N.; Bouchard, L. S.; Liu, M. L.; Zhou, X., Biothiol Xenon MRI Sensor Based on Thiol-Addition Reaction. Analytical Chemistry 2016, 88(11), 5835-5840. 

37. Zhai, Z. N.; Wu, Q.; Zheng, W. W.; Liu, M. L.; Pielak, G. J.; Li, C. G., Roles of structural plasticity in chaperone HdeA activity are revealed by F-19 NMR. Chemical Science 2016, 7(3), 2222-2228. 

38. Jiang, B.; Yu, B. H.; Zhang, X.; Liu, M. L.; Yang, D. W., A N-15 CPMG relaxation dispersion experiment more resistant to resonance offset and pulse imperfection. Journal of Magnetic Resonance 2015, 257, 1-7.

39. Liu, M. L., Probing single protein with electron spin resonance in combination with shallow nitrogen vacancy. Science China-Chemistry 2015, 58 (5), 833-833.

40. Liu, Y. X.; Mao, X.-a.; Liu, M. L.; Jiang, L., Beryllium Fluoride Exchange Rate Accelerated by Mg2+ as Discovered by F-19 NMR. Journal of Physical Chemistry A 2015, 119 (1), 24-28.

41. Fang, Y.; Duan, B.; Lu, A.; Liu, M. L.; Liu, H. L.; Xu, X. J.; Zhang, L. N., Intermolecular Interaction and the Extended Wormlike Chain Conformation of Chitin in NaOH/Urea Aqueous Solution. Biomacromolecules 2015, 16 (4), 1410-1417.

42. He, Y. G.; Feng, J. W.; Zhang, Z.; Wang, C.; Wang, D.; Chen, F.; Liu, M. L.; Liu, C. Y., A peripheral component interconnect express-based scalable and highly integrated pulsed spectrometer for solution state dynamic nuclear polarization. The Review of scientific instruments 2015, 86 (8), 083101-083101.

43. Ren, L. L.; Chen, S. Z.; Li, H. D.; Zhang, Z. Y.; Ye, C. H.; Liu, M. L.; Zhou, X., MRI-visible liposome nanovehicles for potential tumor-targeted delivery of multimodal therapies. Nanoscale 2015, 7 (30), 12843-12850.

44. Ye, Y. S.; Liu, X. L.; Chen, Y. H.; Xu, G. H.; Wu, Q.; Zhang, Z. T.; Yao, C. D.; Liu, M. L.; Li, C. G., Labeling Strategy and Signal Broadening Mechanism of Protein NMR Spectroscopy in Xenopus laevis Oocytes. Chemistry-a European Journal 2015, 21 (24), 8686-8690.

45. Ye, Y. S.; Liu, X. L.; Xu, G. H.; Liu, M. L.; Li, C. G., Direct Observation of Ca2+-Induced Calmodulin Conformational Transitions in Intact Xenopus laevis Oocytes by F-19 NMR Spectroscopy. Angewandte Chemie-International Edition 2015, 54 (18), 5328-5330. 

46. Zhu, X. L.; Chen, S. Z.; Luo, Q.; Ye, C. H.; Liu, M. L.; Zhou, X., Body temperature sensitive micelles for MRI enhancement. Chemical Communications 2015, 51 (44), 9085-9088.

47. Zhang, Y.; Yang, H. R.; Guo, X.; Rong, N. Y.; Song, Y. J.; Xu, Y. W.; Lan, W. X.; Zhang, X.; Liu, M. L.; Xu, Y. H.; Cao, C. Y., The PHD1 finger of KDM5B recognizes unmodified H3K4 during the demethylation of histone H3K4me2/3 by KDM5B. Protein & Cell 2014, 5 (11), 837-850.

48. Liu, Y. X.; Mao, X. A.; Liu, M. L.; Jiang, L., Impact of Magnesium(II) on Beryllium Fluorides in Solutions Studied by F-19 NMR Spectroscopy. Chinese Journal of Chemistry 2014, 32 (9), 878-882. 

49. Lan, W. X; Wang, Z. H.; Yang, Z. Z.; Ying, T. L.; Zhang, X.; Tan, X. S.; Liu, M. L.; Cao, C. Y.; Huang, Z. X., Structural Basis for Cytochrome c Y67H Mutant to Function as a Peroxidase. Plos One 2014, 9 (9).

50. Du, T. P.; Jiang, L.; Liu, M. L., NMR structures of fusion peptide from influenza hemagglutinin H3 subtype and its mutants. Journal of Peptide Science 2014, 20 (4), 292-297.

51. Xu, G. H.; Ye, Y. S.; Liu, X. L.; Cao, S. F.; Wu, Q.; Cheng, K.; Liu, M. L.; Pielak, G. J.; Li, C. G., Strategies for Protein NMR in Escherichia coli. Biochemistry 2014, 53 (12), 1971-1981.

53. Zhang, J.; Jiang, W. P.; Luo, Q.; Zhang, X. X.; Guo, Q. N.; Liu, M. L.; Zhou, X., Rational design of hyperpolarized xenon NMR molecular sensor for the selective and sensitive determination of zinc ions. Talanta 2014, 122, 101-105.

53. Zhang, Z. T.; Dai, C. Y.; Bai, J.; Xu, G. H.; Liu, M. L.; Li, C. G., Ca2+ modulating alpha-synuclein membrane transient interactions revealed by solution NMR spectroscopy. Biochimica Et Biophysica Acta-Biomembranes 2014, 1838 (3), 853-858. 

54. Chen, S. Z.; Yang, Y. Q.; Li, H. D.; Zhou, X.; Liu, M. L., pH-Triggered Au-fluorescent mesoporous silica nanoparticles for F-19 MR/fluorescent multimodal cancer cellular imaging. Chemical Communications 2014, 50 (3), 283-285.

55. Hou, Z. Y.; Zhang, Z. H. ; Meng, H. M.; Lin, X. T.; Sun, B.; Lei, H.; Fang, K.; Fang, F.; Liu, M. L.; Liu, S. W., Parkinson's disease: in vivo metabolic changes in the frontal and parietal cortices in 6-OHDA treated rats during different periods. International Journal of Neuroscience 2014, 124 (2), 125-132. 

56. Jiang, Z.; Liu, J.; Sun,K.; Dong, J. F.; Li, X. F.; Mao, S. Z.; Du, Y. R.; Liu, M. L., pH- and concentration-induced micelle-to-vesicle transitions in pyrrolidone-based Gemini surfactants. Colloid and Polymer Science 2014, 292 (3), 739-747.

57. Wang, G. F.; Zhang, Z. T.; Jiang, B.; Zhang, X.; Li, C. G.; Liu, M. L., Recent advances in protein NMR spectroscopy and their implications in protein therapeutics research. Analytical and Bioanalytical Chemistry 2014, 406 (9-10), 2279-2288.








 
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