膜蛋白结构与功能组
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Prof. Dr. Jun Yang

 Xiaohongshan Road, 30#

Wuhan Institute of Physics and Mathematics,

Chinese Academy of Sciences

Wuhan, Hubei, 430071

P.R.China

E-mail: yangjun(at)wipm.ac.cn

Education & Positions

2010 - Present, Wuhan Institute of Physics and Mathematics, P.R. China, Professor

2008 - 2010, Goethe University (Prof. Clemens Glaubitz), Germany, Research Scholar

2006 - 2008, University of Delaware (Prof. Tatyana Polenova), USA, Postdoctoral Fellow

2003 - 2006, Wuhan Institute of Physics and Mathematics, P.R. China, Associate Professor

2000 - 2003, Wuhan Institute of Physics and Mathematics, P.R. China, Ph.D.

Research Interests

1. Development of solid-state MAS NMR methods and techniques;

2. Structures, dynamics and functions of membrane proteins and amyloid fibrils by solid-state MAS NMR

Selected Publications

1.  ZF Zhang#, YK Chen#, XQ Tang, JP Li, LY Wang, J Yang*, Solid-State NMR Shows That Dynamically Different Domains of Membrane Proteins Have Different Hydration Dependence, J. Phys. Chem. B, 118 (2014) 9553-9564.

2.  Z Niu#, WJ Zhao#, ZF Zhang#, FS Xiao, XQ Tang, J Yang*, The Molecular Structure of Alzheimer's β-Amyloid Fibrils Induced by Phospholipid Vesicles, Angew. Chem. Int. Ed., 53 (2014) 9294-9297.

3. YK Chen#, ZF Zhang#, XQ Tang, JP Li, C Glaubitz, J Yang*, Conformation and Topology of Diacylglycerol Kinase in E. coli Membranes Revealed by Solid-state NMR Spectroscopy, Angew. Chem. Int. Ed., 53 (2014) 5624-5628.

4. ZF Zhang, RQ Fu, JP Li, J Yang*, Asymmetric simultaneous phase-inversion cross-polarization in solid-state MAS NMR: Relaxing selective polarization transfer condition between two dilute spins, J. Magn. Reson., 242 (2014) 214-219.

5. JP Li, KB Pilla, QF Li, ZF Zhang, XC Su, T Huber, J Yang*, Magic Angle Spinning NMR Structure Determination of Proteins from Pseudocontact Shifts, J. Am. Chem. Soc., 135 (2013) 8294-8303.

6.  ZF Zhang, YM Miao, XL Liu, J Yang*, CG Li, F Deng, RQ Fu*, Dual-band selective double cross polarization for heteronuclear polarization transfer between dilute spins in solid-state MAS NMR, J. Magn. Reson., 217 (2012) 92-99.

7.  Yang J*, Aslimovska L, Glaubitz C*,Molecular dynamics of proteorhodopsin in lipid bilayers by solid-state NMR, J. Am. Chem. Soc., 133 (2011),4874–4881.

8.  Han Y,Ahn J, Concel J, Byeon IJ, Gronenborn AM, Yang J, Polenova T*, Solid-State NMR Studies of HIV-1 Capsid Protein Assemblies, J. Am. Chem. Soc., 132 (2010), 1976-1987.

9.  Yang J, Tasayco ML, Polenova T*, Dynamics of reassembled thioredoxin studied by magic angle spinning NMR: snapshots from different timescales, J. Am. Chem. Soc.,131 (2009), 13690-13702.

10.  Pfleger N, Woerner AC, Yang J, Shastri S, Hellmich A, Aslimovska L, Maier M, Glaubitz C*, Solid-state NMR and functional studies on proteorhodopsin, BBA Bioenergetics, 1787 (2009), 697-705.

11.  Yang J, Tasayco ML, Polenova T*, Magic Angle Spinning NMR Experiments for Structural Studies of Differentially Enriched Protein Interfaces and Protein Assemblies, J. Am. Chem. Soc., 130 (2008), 5798–5807.

Research Group








 
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